Matthew Bernier, PhD

I am the small molecule, accurate mass, and metabolomics facilitator here at the Mass Spectrometry and Proteomics Facility. My work here at the facility began in early 2017 after first finishing my PhD with Vicki Wysocki at Ohio State in 2014 and doing Post-Doctoral work at Georgia Tech with Dr. Facundo Fernandez. My main research areas of focus have mainly involved small molecule peptide fragmentation fundamentals, ambient ionization development, and high-resolution analysis. I have experience working with small molecule analysis of complex mixtures from many sources and have used many instrument platforms from GCMS to ICR along with small molecule analysis with ion mobility on Waters Synapt G2 instrumentation. In the facility, I use mainly the ThermoScientific Quantiva triple quadrupole for targeted metabolomics and the Thermo Q-Exactive plus for untargeted metabolomics for the majority of projects. I also train users in the operation of the triple quadrupole, the GCMS Thermo DSQ instrument, and run accurate mass analysis on our 15 T Bruker ICR. In addition, for both targeted and untargeted small molecule metabolomics I use our data analysis programs, particularly Progenesis and other open source software, to identify targets of interest and perform the appropriate statistical analysis for the highest quality data for submitted projects.