Rates

Mass spectrometry and proteomics rates: comprehensive pricing information.

We offer three pricing tiers:

  • Internal: For Ohio State and Consortium members (including Nationwide Children's Hospital)
  • External Academic: For non-profit and academic institutions outside the OH Consortium
  • External Industry: For industry partners

FY2025

Effective as of July 1, 2024

Molecular weight/Chemical Formula determination

  • Accurate mass: $55
  • Nominal mass: $40

Metabolomics

Method Development

  • Qualitative/Untargeted: $1,200 per project
  • Quantitative/Targeted: $1,300 per project
  • Metabolite extraction/sample cleanup: $55 per hour

Sample Analysis

  • Targeted LC-MS/MS: $120 per injection
  • Untargeted LC-MS/MS: $140 per injection

Imaging/Tissue

  • MALDI imaging: $55 per hour
  • Use of Ambergen probes for imaging, at cost by quote (or user-supplied)

Self operation and Staff time (per hour)

  • Self operation tissue preparation, Cryostat and TM Sprayer (min 1/2 hr increments): $10.00 per hour
  • Self operation Amazon (min 1/2 hr increments): $6.00 per hour
  • Self operation MALDI TOF-TOF, Quantiva (min 1/2 hour increments): $20.00 per hour
  • Self operation QE-M, QE-P, Fusion, FT-ICR, Agilent, Exploris_480 (min 1/2 hour increments): $25.00 per hour
  • Self operation timsTOF Pro, timsTOF Flex (min 1/2 hour increments): $25.00 per hour
  • Staff time (consultation, sample/tissue prep, training, min 1/2 hour increments): $55.00 per hour
  • Data Analysis Staff time (custom database setup, additional database searches, archived data retrieval and researching, extensive data mining): $55.00 per hour

Proteomics

  • Albumin removal: $55.00 per sample
  • Peptide/Protein Enrichment (e.g., Phosphorylation): $55.00 per sample
  • Cell Lysis: $45.00 per sample
  • Enzyme Digestion (in solution and in gel): $35.00 per sample
  • S-trap digestion (per digestion): $50.00 per sample
  • Protein Precipitation (per sample): $20.00 per sample
  • Protein Quantitation (nanodrop), Peptide desalting: $10.00 per sample
  • Buffer Exchange: $30.00 per sample
  • Off-line spin column fractionation or buffer exchange: $50.00 per sample
  • Cryomill: $5.00 per sample
  • Lyophylizer: $5.00 per use

Sample Analysis

  • LC-MS/MS peptide sequencing (High complexity e.g. tissue or whole cell lysate): $250.00 per sample
  • LC-MS/MS peptide sequencing (Intermediate complexity e.g. IP samples): $200.00 per sample
  • LC-MS/MS peptide sequencing (Low complexity e.g. gel band): $150.00 per sample
  • LC-MS/MS - 2D or off line LC Fractions per fraction: $150.00 per fraction
  • Top-Down Proteomics (Fusion, QE-P, FT-ICR): $300.00 per sample
  • Quantitation (TMT labeling): By Quote
  • Native Mass Spectrometry: $55.00 per sample

FY2026

Effective as of July 1, 2025

Molecular weight/Chemical Formula determination

  • Accurate mass (ESI, MALDI): $55/sample
  • Nominal mass (MALDI): $40/sample

Metabolomics

Method Development

  • Qualitative/Untargeted: $1,200/project
  • Quantitative/Targeted: $1,300/project

Sample Analysis

  • Metabolite extraction/sample cleanup: $55/hour
  • Targeted LC-MS/MS (<5 compounds): $100/injection
  • Targeted LC-MS/MS (5-10 compounds): $120/injection
  • Targeted LC-MS/MS (>10 compounds): $145/injection
  • Untargeted LC-MS/MS (high-throughput): $100/injection
  • Untargeted LC-MS/MS: $140/injection

Imaging/Tissue

  • MALDI imaging: $55/hour
  • Use of Ambergen probes for imaging: By Quote (or user-supplied)
  • Tissue preparation, cryostat sectioning, TM matrix sprayer (min 1/2 hour increments): $55/hour

Self-operation and Staff time

  • Self-operation tissue preparation, Cryostat and TM Sprayer (min 1/2 hour increments): $10/hour
  • Self-operation Mass Photometer (min 1/2 hour increments): $15/hour
  • Self-operation QE UHMR (min 1/2 hour increments): $25/hour
  • Self-operation MALDI TOF-TOF (min 1/2 hour increments): $20/hour
  • Self-operation QqQ, QE-M, QE-P, Fusion (min 1/2 hour increments): $25/hour
  • Self-operation Eclipse, Exploris 480, timsTOF Pro, ICR (min 1/2 hour increments): $30/hour
  • Self-operation timsTOF Flex (min 1/2 hour increments): $25/hour
  • Staff time (min 1/2 hour increments): $55/hour

Proteomics

  • Protein depletion or enrichment: $55/sample
  • Tissue homogenization and lysis: $50/sample
  • Cell lysis: $30/sample
  • Enzyme digestion (in solution): $30/sample
  • Enzyme digestion (in gel): $40/sample
  • S-trap digestion: $50/sample
  • Protein precipitation: $20/sample
  • Protein quantitation (nanodrop): $5/sample
  • Peptide desalting: $15/sample
  • Off-line spin column fractionation: $50/sample
  • Buffer exchange: $30/sample

Sample Analysis

  • LC-MS/MS peptide sequencing (High complexity e.g. tissue or whole cell lysate): $250/sample
  • LC-MS/MS peptide sequencing (Intermediate complexity e.g. IP samples): $200/sample
  • LC-MS/MS peptide sequencing (Low complexity e.g. gel band): $150/sample
  • LC-MS/MS - 2D or off line LC Fractions: $150/fraction
  • Top-Down Proteomics: By Quote
  • Quantitation (TMT labeling): By Quote
  • Native Mass Spectrometry: $55/sample

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Mass Spectrometry and Proteomics