MS Imaging

Providing users with access to state-of-the-art instrumentation and analysis for visualization of molecules across specimens

Services

Our facility provides label free imaging services using state-of-the-art equipment, including:

  • Sample preparation
    • We offer full sample preparation including embedding, sectioning, and matrix deposition.
  • Label free imaging of lipids and other small molecules in tissues
    • MS imaging can show localization of molecules within different regions of a sample. Accurate mass analysis, combined with fragmentation and/or ion mobility can provide identification for these molecules.
  • Protein imaging
    • We offer protein imaging either using protein digests and identifying the peptides, or using chemical probes.

 

State-of-the-art instrumentation

Our imaging instrumentation includes:

  • Bruker timsTOF fleX with MALDI-2
  • Bruker 15T FT-ICR 
  • Bruker ultrafleXtreme MALDI TOF-TOF

Additional Information

Schedule a meeting with our imaging team to help design and implement your research project. Please contact ccic-msp@osu.edu
Mass Spectrometry and Proteomics